VPS37B and FBF1

Data Source:
BioGRID (two hybrid)

		VPS37B	FBF1
Description		VPS37B subunit of ESCRT-I	Fas binding factor 1
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT I Complex Cytoplasm Endosome Plasma Membrane Endosome Membrane Midbody Late Endosome Membrane Intracellular Membrane-bounded Organelle Host Cell Extracellular Exosome	Spindle Pole Centrosome Centriole Cytosol Ciliary Basal Body Apical Junction Complex Keratin Filament Ciliary Transition Fiber
	Molecular Function	Protein Binding Calcium-dependent Protein Binding	Protein Binding
	Biological Process	Protein Targeting To Membrane Protein Targeting To Vacuole Endosomal Transport Macroautophagy Viral Life Cycle Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Intracellular Transport Of Virus Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Viral Budding Via Host ESCRT Complex	Apical Junction Assembly Cilium Assembly Establishment Of Epithelial Cell Polarity Ciliary Basal Body-plasma Membrane Docking
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy	Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Tourette syndrome ( 30818990)	Coronary artery disease ( 29212778) White matter hyperintensity burden ( 25663218)
Interacting Genes		25 interacting genes: BAG3 BYSL CDC73 DCUN1D1 ENKD1 ERCC1 EXOC8 FBF1 GORASP2 HGS KDM1A LNX1 NCK2 OSTF1 PRKAA1 PRKAA2 QARS1 SH3YL1 SMARCD1 SORBS3 TLE5 TSG101 UBASH3A UBASH3B VPS28	49 interacting genes: ABI3 ACCS APP BLZF1 CALCOCO2 CCDC102B CCDC85B CEP55 CEP63 CINP CLK1 DEUP1 DGCR6 FAS FBXL12 GATA1 GCC1 GOLGA2 HIF1AN IFT20 IKZF3 KRT13 KRT31 KRT40 MEOX2 MID2 MIPOL1 PNMA1 RBPMS RHOXF2 SSX2IP SUMO1 TADA2A TASOR2 TCEA2 TEX11 TLE5 TMCC2 TRAF1 TRAF2 TRIM23 TRIM27 TRIM29 TRIM54 TSGA10 TTC32 TUBGCP4 USHBP1 VPS37B
Entrez ID		79720	85302
HPRD ID		07794	10948
Ensembl ID		ENSG00000139722	ENSG00000188878
Uniprot IDs		A0A024RBU0 Q9H9H4	Q8TES7
PDB IDs		6VME
Enriched GO Terms of Interacting Partners?
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