KRTAP4-1 and FBXW5

Data Source:
BioGRID (two hybrid)

		KRTAP4-1	FBXW5
Description		keratin associated protein 4-1	F-box and WD repeat domain containing 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function		Protein Binding Protein Kinase Binding
	Biological Process	Keratinization	Protein Polyubiquitination Regulation Of Mitotic Nuclear Division Regulation Of Centrosome Duplication Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification
Pathways		Keratinization	Association of TriC/CCT with target proteins during biosynthesis Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Blood protein levels ( 29875488) Heel bone mineral density ( 30598549) Plateletcrit ( 32888494)
Interacting Genes		26 interacting genes: CATSPER1 CRCT1 CREB5 DHRS1 FBXW5 GNE HOXA1 IL10 KRTAP5-6 KRTAP9-3 KRTAP9-8 LCE1B LCE1D LCE2D LCE3A LCE3C LCE3D LCE3E LCE5A NECTIN3 NPDC1 NUFIP2 OTX1 PSMA1 SMCP VASN	35 interacting genes: ADAMTSL4 CYSRT1 EFEMP2 FAM168A FBLN2 KRT31 KRT34 KRT37 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-1 KRTAP4-12 KRTAP6-3 KRTAP9-3 KRTAP9-4 MDFI MID2 MTUS2 MYB NBPF19 NLK NOTCH2NLA PLEKHF2 S100B SASS6 SEC23B SKP1 TRIM27 TSC2 UBE2R2 VWC2
Entrez ID		85285	54461
HPRD ID		13940	10955
Ensembl ID		ENSG00000198443	ENSG00000159069
Uniprot IDs		Q9BYQ7	A0A024R8H7 Q969U6
PDB IDs
Enriched GO Terms of Interacting Partners?
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