FBXW5 and KRTAP9-4

Data Source:
BioGRID (two hybrid)

		FBXW5	KRTAP9-4
Description		F-box and WD repeat domain containing 5	keratin associated protein 9-4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex	Cytosol Keratin Filament
	Molecular Function	Protein Binding Protein Kinase Binding	Protein Binding
	Biological Process	Protein Polyubiquitination Regulation Of Mitotic Nuclear Division Regulation Of Centrosome Duplication Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification	Keratinization
Pathways		Association of TriC/CCT with target proteins during biosynthesis Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Keratinization
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Heel bone mineral density ( 30598549) Plateletcrit ( 32888494)
Interacting Genes		35 interacting genes: ADAMTSL4 CYSRT1 EFEMP2 FAM168A FBLN2 KRT31 KRT34 KRT37 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-1 KRTAP4-12 KRTAP6-3 KRTAP9-3 KRTAP9-4 MDFI MID2 MTUS2 MYB NBPF19 NLK NOTCH2NLA PLEKHF2 S100B SASS6 SEC23B SKP1 TRIM27 TSC2 UBE2R2 VWC2	29 interacting genes: ADAMTSL4 CATSPER1 CREB5 DHX57 DOCK2 FBXW5 HOXA1 KRTAP10-1 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE1B LCE3C LCE3E LCE4A MAPKBP1 NOTCH2NLA NTAQ1 NUFIP2 OTX1 PRKAB2 REL SMCP SPRY2 YIPF3
Entrez ID		54461	85280
HPRD ID		10955	13951
Ensembl ID		ENSG00000159069	ENSG00000241595
Uniprot IDs		A0A024R8H7 Q969U6	Q9BYQ2
PDB IDs
Enriched GO Terms of Interacting Partners?
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