IFITM1 and CR2

Data Source:
HPRD (in vivo)

		IFITM1	CR2
Description		interferon induced transmembrane protein 1	complement C3d receptor 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Protein-containing Complex	Plasma Membrane Integral Component Of Membrane Receptor Complex Extracellular Exosome
	Molecular Function	Protein Binding	Virus Receptor Activity Complement Binding DNA Binding Complement Receptor Activity Transmembrane Signaling Receptor Activity Protein Binding Protein Homodimerization Activity
	Biological Process	Ossification Cell Surface Receptor Signaling Pathway Negative Regulation Of Cell Population Proliferation Response To Virus Negative Regulation Of Cell Migration Response To Interferon-gamma Response To Interferon-alpha Response To Interferon-beta Negative Regulation Of Viral Genome Replication Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Viral Entry Into Host Cell Regulation Of Immune Response Defense Response To Virus Type I Interferon Signaling Pathway	Complement Receptor Mediated Signaling Pathway Immune Response Complement Activation, Alternative Pathway Complement Activation, Classical Pathway B Cell Differentiation Regulation Of Complement Activation B Cell Proliferation Viral Entry Into Host Cell
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Interferon alpha/beta signaling	Regulation of Complement cascade
Drugs
Diseases
GWAS			Alzheimer's disease or fasting insulin levels (pleiotropy) ( 30805717) Refractive error ( 32231278) Systemic sclerosis ( 29293537) Type 2 diabetes ( 21490949)
Interacting Genes		3 interacting genes: ABHD16A CD81 CR2	10 interacting genes: ANXA6 C3 CD19 CR1 FCER2 FHOD1 HNRNPU IFITM1 IFNA1 TP53
Entrez ID		8519	1380
HPRD ID		05122	00399
Ensembl ID		ENSG00000185885	ENSG00000117322
Uniprot IDs		A0A024R210 P13164	P20023
PDB IDs			1GHQ 1LY2 1W2R 1W2S 2ATY 2GSX 3OED
Enriched GO Terms of Interacting Partners?
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