PRPF38A and SRSF4

Data Source:
BioGRID (two hybrid, two hybrid)

		PRPF38A	SRSF4
Description		pre-mRNA processing factor 38A	serine and arginine rich splicing factor 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm U2-type Precatalytic Spliceosome Precatalytic Spliceosome	Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	RNA Binding Protein Binding	RNA Binding MRNA Binding Protein Binding Sequence-specific MRNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Response To Insulin Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Major Pathway	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs			Artenimol
Diseases
GWAS			Carotid plaque maximum area ( 32469969) Hematocrit ( 32888494) Hemoglobin ( 32888494) Mean area of carotid plaque ( 32469969) Schizophrenia ( 26531332) Tourette syndrome ( 30818990)
Interacting Genes		24 interacting genes: AP2M1 APP CHERP CLK1 CLK2 CSNK2A1 DHX8 DVL3 GTF3C1 JMJD6 MAPK6 POLA2 PPIG PRMT5 RBM39 RNPS1 SDCBP SDCBP2 SRPK1 SRPK2 SRSF4 SRSF7 U2AF1 ZCCHC10	24 interacting genes: DYRK1A FUS GEMIN2 HAP1 HTATSF1 PNN PPARGC1A PRPF38A RNPS1 SART1 SCAF11 SMURF1 SMURF2 SREK1 SRPK1 SRRM2 SRSF1 SRSF10 SRSF2 SRSF6 TICAM1 TRA2B UBE2I ZDHHC17
Entrez ID		84950	6429
HPRD ID		10972	09052
Ensembl ID		ENSG00000134748	ENSG00000116350
Uniprot IDs		Q8NAV1	Q08170
PDB IDs		4RZ9 4RZA 5F5S 5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
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