OGT and TRAK2

Data Source:
HPRD (in vitro)

		OGT	TRAK2
Description		O-linked N-acetylglucosamine (GlcNAc) transferase	trafficking kinesin protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytosol Plasma Membrane Protein N-acetylglucosaminyltransferase Complex Mitochondrial Membrane Protein-containing Complex Cell Projection	Nucleus Cytoplasm Mitochondrion Early Endosome Plasma Membrane Dendrite Cytoplasmic Vesicle Dendrite Cytoplasm Neuronal Cell Body Axonal Growth Cone Axon Cytoplasm
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Acetylglucosaminyltransferase Activity Protein N-acetylglucosaminyltransferase Activity Protein O-GlcNAc Transferase Activity	Signaling Receptor Binding Protein Binding Myosin Binding Kinesin Binding Enzyme Binding TPR Domain Binding GABA Receptor Binding
	Biological Process	Regulation Of Glycolytic Process Regulation Of Gluconeogenesis Regulation Of Transcription By RNA Polymerase II Protein O-linked Glycosylation Apoptotic Process Signal Transduction Response To Nutrient Viral Process Protein Processing Protein Deubiquitination Protein Phosphopantetheinylation Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Insulin Circadian Regulation Of Gene Expression Regulation Of Rac Protein Signal Transduction Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Proteolysis Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Positive Regulation Of Histone H3-K27 Methylation Histone H3-K4 Trimethylation Positive Regulation Of Cold-induced Thermogenesis	Regulation Of Transcription By RNA Polymerase II Protein O-linked Glycosylation Protein Targeting Endosome To Lysosome Transport Neurogenesis Vesicle Transport Along Microtubule Mitochondrion Distribution Dendrite Morphogenesis Negative Regulation Of Axonogenesis Anterograde Axonal Transport Of Mitochondrion Anterograde Dendritic Transport Of Mitochondrion
Pathways		HATs acetylate histones RIPK1-mediated regulated necrosis Regulation of necroptotic cell death UCH proteinases
Drugs
Diseases
GWAS		Red cell distribution width ( 32888494)	Breast cancer ( 31757997) Cocaine use disorder x change in residence interaction ( 31490055)
Interacting Genes		28 interacting genes: CSNK2A1 CSNK2B GSK3B HCFC1 HIRA HIVEP1 MAPT MTDH NUP62 NUP62CL OGA PHC3 PSG1 SAP30BP SCAI SIN3A SNAP91 SP1 SRF TAB1 TAB3 TET2 TRAF7 TRAK1 TRAK2 UBC YES1 ZNF124	3 interacting genes: GABRB2 KCNJ2 OGT
Entrez ID		8473	66008
HPRD ID		02222	09547
Ensembl ID		ENSG00000147162	ENSG00000115993
Uniprot IDs		O15294	O60296
PDB IDs		1W3B 3PE3 3PE4 3TAX 4AY5 4AY6 4CDR 4GYW 4GYY 4GZ3 4GZ5 4GZ6 4N39 4N3A 4N3B 4N3C 4XI9 4XIF 5BNW 5C1D 5HGV 5LVV 5LWV 5NPR 5NPS 5VIE 5VIF 6E37 6EOU 6IBO 6MA1 6MA2 6MA3 6MA4 6MA5 6Q4M 6TKA
Enriched GO Terms of Interacting Partners?
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