KISS1R and PTPA

Data Source:
BioGRID (pull down)

		KISS1R	PTPA
Description		KISS1 receptor	protein phosphatase 2 phosphatase activator
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cilium Cell Surface Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Protein Phosphatase Type 2A Complex Nucleus Nucleoplasm Cytoplasm Calcium Channel Complex Extracellular Exosome
	Molecular Function	Protein Binding Neuropeptide Receptor Activity G Protein-coupled Peptide Receptor Activity	Peptidyl-prolyl Cis-trans Isomerase Activity Signaling Receptor Binding Protein Binding ATP Binding Protein Tyrosine Phosphatase Activator Activity ATPase Activity Protein Phosphatase Regulator Activity Protein Homodimerization Activity Protein Phosphatase 2A Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway	Protein Peptidyl-prolyl Isomerization Mitotic Spindle Organization Negative Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Protein Dephosphorylation Positive Regulation Of Apoptotic Process Regulation Of Phosphoprotein Phosphatase Activity
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events
Drugs		ANZ-100
Diseases		Precocious puberty, including: Central precocious puberty (CEPREPU); Familial male precocious puberty (FMPP) Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS		Menopause (age at onset) ( 26414677) Sweet taste preference ( 32572145)
Interacting Genes		3 interacting genes: KISS1 PPP2CA PTPA	28 interacting genes: AKT1 AMOT APP AURKB CCDC125 CCNE1 CCNG1 CCNG2 CSNK2A1 CYLD DTD1 EIF4EBP1 F3 FOXO3 GRIN3A H2AX HDAC4 KISS1R MAPT MID1 NIF3L1 PPP2R1A PPP2R3A PRKCB RACGAP1 SPG21 SRC SULT4A1
Entrez ID		84634	5524
HPRD ID		09167	02858
Ensembl ID		ENSG00000116014	ENSG00000119383
Uniprot IDs		Q969F8 U3KQ86	B4DZF8 F6WIT2 Q15257
PDB IDs			2G62 2HV6 2HV7 2IXM 4LAC 4NY3
Enriched GO Terms of Interacting Partners?
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