HOPX and EPC1

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		HOPX	EPC1
Description		HOP homeobox	enhancer of polycomb homolog 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm	Nucleus Nucleoplasm Nuclear Membrane Piccolo NuA4 Histone Acetyltransferase Complex NuA4 Histone Acetyltransferase Complex Intracellular Membrane-bounded Organelle
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding	Histone Acetyltransferase Activity Protein Binding
	Biological Process	Trophectodermal Cell Differentiation Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Differentiation Chaperone-mediated Protein Complex Assembly	Negative Regulation Of Transcription By RNA Polymerase II Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Vascular Associated Smooth Muscle Cell Differentiation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G0 To G1 Transition
Pathways			HATs acetylate histones Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Cadmium levels ( 26025379) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systemic sclerosis ( 30247649)	Diastolic blood pressure ( 30224653) Metabolite levels ( 23823483) Platelet distribution width ( 32888494 27863252) Sexual dysfunction (female) ( 22509378)
Interacting Genes		9 interacting genes: EPC1 HDAC2 HOXB9 PICK1 PTGER4 SRF TCF12 TLX3 ZSCAN1	9 interacting genes: CHRM5 E2F6 HOPX KAT5 KRT15 MBTD1 RINT1 SYCE1L TRIM27
Entrez ID		84525	80314
HPRD ID		06280	09941
Ensembl ID		ENSG00000171476	ENSG00000120616
Uniprot IDs		Q9BPY8	Q9H2F5
PDB IDs			6NFX
Enriched GO Terms of Interacting Partners?
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