EPC1 and SYCE1L

Data Source:
BioGRID (two hybrid)

		EPC1	SYCE1L
Description		enhancer of polycomb homolog 1	synaptonemal complex central element protein 1 like
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Membrane Piccolo NuA4 Histone Acetyltransferase Complex NuA4 Histone Acetyltransferase Complex Intracellular Membrane-bounded Organelle	Synaptonemal Complex Intermediate Filament Cytoskeleton
	Molecular Function	Histone Acetyltransferase Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Vascular Associated Smooth Muscle Cell Differentiation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G0 To G1 Transition	Synaptonemal Complex Assembly
Pathways		HATs acetylate histones Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Metabolite levels ( 23823483) Platelet distribution width ( 32888494 27863252) Sexual dysfunction (female) ( 22509378)	Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		9 interacting genes: CHRM5 E2F6 HOPX KAT5 KRT15 MBTD1 RINT1 SYCE1L TRIM27	36 interacting genes: ALDH18A1 ANKRD36 ATF5 BFSP2 BOLL C1orf216 C22orf39 CALN1 CCDC146 CCDC196 CCHCR1 CENPP CST1 CYTH4 DPPA3 EPC1 FGA HSF2BP KCNIP2 KIAA1328 LCA5L LNX1 MED10 NOL4 NTAQ1 ODF1 OIP5 PFDN5 SCHIP1 SLC7A8 SMARCD1 SPHKAP SRSF10 TNNI1 TRAPPC13 ZNF526
Entrez ID		80314	100130958
HPRD ID		09941
Ensembl ID		ENSG00000120616	ENSG00000205078
Uniprot IDs		Q9H2F5	A8MT33
PDB IDs		6NFX
Enriched GO Terms of Interacting Partners?
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