FBN3 and RPN2

Data Source:
BioGRID (two hybrid)

		FBN3	RPN2
Description		fibrillin 3	ribophorin II
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Matrix Collagen-containing Extracellular Matrix	Autophagosome Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Oligosaccharyltransferase Complex Membrane Integral Component Of Membrane Nuclear Body
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding	Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding Ribosome Binding
	Biological Process	Anatomical Structure Morphogenesis	Cellular Protein Modification Process Protein N-linked Glycosylation Aging Protein N-linked Glycosylation Via Asparagine Response To Drug
Pathways		Degradation of the extracellular matrix Elastic fibre formation Molecules associated with elastic fibres Molecules associated with elastic fibres	SRP-dependent cotranslational protein targeting to membrane Asparagine N-linked glycosylation Maturation of spike protein
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Attention deficit hyperactivity disorder ( 30563984) Blood protein levels ( 28240269) Neurocognitive impairment in HIV-1 infection (continuous) ( 28447399) Pre-treatment viral load in HIV-1 infection ( 31219150) Refractive error ( 32231278) Serum metabolite ratios in chronic kidney disease ( 29545352)	Height ( 31562340) Hippocampal atrophy ( 19668339) Initial pursuit acceleration in psychotic disorders ( 29064472)
Interacting Genes		13 interacting genes: ANXA7 BID C11orf58 CDKN1A DAZAP2 GADD45A GSK3B NUDT21 PIK3R3 RPN2 RPS6KA6 TK1 TSC22D1	12 interacting genes: ADRM1 EZH2 FBN3 LTB4R2 NDRG1 NGFR PTEN RBBP4 RCHY1 RHOA SLC22A2 SMO
Entrez ID		84467	6185
HPRD ID		10538	01609
Ensembl ID		ENSG00000142449	ENSG00000118705
Uniprot IDs		A0A494C0D8 A8KAY2 Q75N90	P04844
PDB IDs			6S7O 6S7T
Enriched GO Terms of Interacting Partners?
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