DUSP11 and SRSF7

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DUSP11	SRSF7
Description		dual specificity phosphatase 11	serine and arginine rich splicing factor 7
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GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Nuclear Speck Intercellular Bridge	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Extracellular Exosome
	Molecular Function	RNA Binding Polynucleotide 5'-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatase Activity Nucleotide Phosphatase Activity, Acting On Free Nucleotides	RNA Binding Protein Binding Zinc Ion Binding Protein Domain Specific Binding
	Biological Process	RNA Processing Protein Dephosphorylation RNA Metabolic Process Peptidyl-tyrosine Dephosphorylation Polynucleotide 5' Dephosphorylation	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Negative Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Leukemia Inhibitory Factor
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Creatinine levels ( 20383145) Lean body mass ( 28552196) Metabolite levels ( 21931564) Serum metabolite levels ( 23093944)
Interacting Genes		3 interacting genes: QARS1 SRSF7 SRSF9	18 interacting genes: CCNL2 CDK19 CDK6 CLK1 CPSF6 DUSP11 FBXO7 LUC7L LUC7L2 NEDD4 NXF1 PCBP2 PRPF38A RNPS1 SDCBP SREK1 SRPK1 SRPK2
Entrez ID		8446	6432
HPRD ID		04368	08991
Ensembl ID		ENSG00000144048	ENSG00000115875
Uniprot IDs		O75319	Q16629
PDB IDs		4JMJ 4MBB 4NYH	2HVZ
Enriched GO Terms of Interacting Partners?
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