BTBD10 and LAMA5

Data Source:
HPRD (two hybrid)

		BTBD10	LAMA5
Description		BTB domain containing 10	laminin subunit alpha 5
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Cytoplasm	Extracellular Region Basement Membrane Laminin-5 Complex Extracellular Space Nucleus Neuromuscular Junction Synaptic Cleft Laminin-10 Complex Laminin-11 Complex Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Protein Binding	Integrin Binding Extracellular Matrix Structural Constituent
	Biological Process	Positive Regulation Of Phosphorylation Type B Pancreatic Cell Proliferation Negative Regulation Of Neuron Death	Branching Involved In Ureteric Bud Morphogenesis Morphogenesis Of A Polarized Epithelium Neural Crest Cell Migration Hair Follicle Development Integrin-mediated Signaling Pathway Axon Guidance Muscle Organ Development Animal Organ Morphogenesis Tissue Development Morphogenesis Of Embryonic Epithelium Cell Migration Cytokine-mediated Signaling Pathway Regulation Of Cell Adhesion Extracellular Matrix Organization Lung Development Regulation Of Cell Migration Substrate Adhesion-dependent Cell Spreading Regulation Of Cell Population Proliferation Odontogenesis Of Dentin-containing Tooth Regulation Of Embryonic Development Cilium Assembly Branching Involved In Salivary Gland Morphogenesis Protein Localization To Plasma Membrane Cell-cell Adhesion
Pathways			Degradation of the extracellular matrix Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans Interleukin-4 and Interleukin-13 signaling MET activates PTK2 signaling
Drugs			Lanoteplase
Diseases
GWAS		Progression free survival in serous epithelial ovarian cancer treated with carboplatin and paclitaxel ( 28935272)	Blood protein levels ( 29875488) Colorectal cancer ( 25990418 20972440 24737748) Colorectal cancer or advanced adenoma ( 30510241) Estimated glomerular filtration rate ( 31152163) Neuroblastoma (pediatric) ( 32599975) Pelvic organ prolapse ( 26545240) Plateletcrit ( 32888494) Prostate cancer ( 23535732)
Interacting Genes		8 interacting genes: ACIN1 CDC37 CUL3 DLG5 LAMA5 MAPK3 PPP1CA PPP1CC	15 interacting genes: ATF7IP BCAM BTBD10 COL7A1 CRKL DAG1 FBLN2 LAMC1 MEP1A MTDH MYOC SMAD2 SV2A UBC USP4
Entrez ID		84280	3911
HPRD ID		17045	03020
Ensembl ID		ENSG00000148925	ENSG00000130702
Uniprot IDs		B7Z503 D3DQW7 Q9BSF8	O15230
PDB IDs			5XAU
Enriched GO Terms of Interacting Partners?
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