POLR3GL and YAF2

Data Source:
BioGRID (two hybrid)

		POLR3GL	YAF2
Description		RNA polymerase III subunit GL	YY1 associated factor 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm RNA Polymerase III Complex Cytosol	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Transcription By RNA Polymerase III Positive Regulation Of Type I Interferon Production	Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		11 interacting genes: BEND7 CCND3 LMO1 M1AP MEOX1 MEOX2 PAX6 POLR3C RBPMS TFCP2 YAF2	29 interacting genes: ANP32B CAVIN1 CD300LF DNAAF6 EAF1 GABPB1 IFT57 INO80B LGALS7 LGALS7B MAPRE3 MARK1 MYC MYCN NEDD8 NUTF2 PCDH17 POLR3GL PPP1R11 RING1 RNF2 SETBP1 SPANXN2 SPANXN3 TLK1 UBC XAGE1B YY1 ZFP42
Entrez ID		84265	10138
HPRD ID		14546	09606
Ensembl ID		ENSG00000121851	ENSG00000015153
Uniprot IDs		A6NGX6 Q9BT43	B4DJQ9 G3V212 Q8IY57
PDB IDs		5AFQ	2D9G
Enriched GO Terms of Interacting Partners?
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