EVA1A and POLE4

Data Source:
HPRD (in vitro)

		EVA1A	POLE4
Description		eva-1 homolog A, regulator of programmed cell death	DNA polymerase epsilon 4, accessory subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Epsilon DNA Polymerase Complex
	Molecular Function	Protein Binding	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	Autophagy Apoptotic Process Post-translational Protein Modification Cellular Protein Metabolic Process	G1/S Transition Of Mitotic Cell Cycle DNA Replication Initiation Telomere Maintenance Via Semi-conservative Replication DNA Biosynthetic Process
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Recognition of DNA damage by PCNA-containing replication complex PCNA-Dependent Long Patch Base Excision Repair Termination of translesion DNA synthesis HDR through Homologous Recombination (HRR) Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER DNA replication initiation Activation of the pre-replicative complex
Drugs			Cladribine
Diseases
GWAS		Chronotype ( 30696823) Gout ( 32238385) Seborrheic dermatitis ( 29203360)
Interacting Genes		8 interacting genes: GYPA MAP1LC3B MS4A13 MTNR1B PTN SAT1 SGTB TSPAN4	7 interacting genes: HSPA13 NFYB POLE POLE2 POLE3 PRKAR1B UBE3A
Entrez ID		84141	56655
HPRD ID		07827	16238
Ensembl ID		ENSG00000115363	ENSG00000115350
Uniprot IDs		Q9H8M9	Q9NR33
PDB IDs
Enriched GO Terms of Interacting Partners?
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