ARL6 and GLS

Data Source:
BioGRID (affinity chromatography technology)

		ARL6	GLS
Description		ADP ribosylation factor like GTPase 6	glutaminase
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GO Annotations	Cellular Component	Cytoplasm Axonemal Microtubule Plasma Membrane Cilium Axoneme Membrane Membrane Coat Extracellular Exosome	Mitochondrion Mitochondrial Matrix Cytosol Synapse
	Molecular Function	GTPase Activity Protein Binding GTP Binding Phospholipid Binding Metal Ion Binding	Glutaminase Activity Protein Binding
	Biological Process	Protein Targeting To Membrane Intracellular Protein Transport Determination Of Left/right Symmetry Visual Perception Wnt Signaling Pathway Vesicle-mediated Transport Melanosome Transport Protein Polymerization Cilium Assembly Protein Localization To Cilium	Suckling Behavior Regulation Of Respiratory Gaseous Exchange By Nervous System Process Glutamate Biosynthetic Process Glutamine Catabolic Process Chemical Synaptic Transmission Cellular Amino Acid Biosynthetic Process Glutamate Secretion Protein Homotetramerization Glutamate Homeostasis
Pathways		BBSome-mediated cargo-targeting to cilium	Glutamate Neurotransmitter Release Cycle TP53 Regulates Metabolic Genes Glutamate and glutamine metabolism
Drugs			Glutamic acid
Diseases		Bardet-Biedl syndrome (BBS) Retinitis pigmentosa (RP)
GWAS		Male infertility ( 19478329)	Chronotype ( 30696823) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494 27863252) JT interval (sulfonylurea treatment interaction) ( 27958378) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		6 interacting genes: ARL6IP1 ARL6IP4 ARL6IP5 ARL6IP6 ATL2 SEC61B	5 interacting genes: ATXN10 CDC42 PARD6A SNTA1 TAX1BP3
Entrez ID		84100	2744
HPRD ID		10588	00700
Ensembl ID		ENSG00000113966	ENSG00000115419
Uniprot IDs		Q9H0F7	O94925 Q68D38
PDB IDs		2H57	3CZD 3UNW 3UO9 3VOY 3VOZ 3VP0 3VP1 3VP2 3VP3 3VP4 4O7D 5D3O 5FI2 5FI6 5FI7 5HL1 5I94 5JYO 5JYP 5U0I 5U0J 5UQE 5WJ6 6UJG 6UJM 6UK6 6UKB 6UL9 6ULA 6ULJ 6UMC 6UMD 6UME 6UMF
Enriched GO Terms of Interacting Partners?
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