NSRP1 and CNR1

Data Source:
BioGRID (pull down)

		NSRP1	CNR1
Description		nuclear speckle splicing regulatory protein 1	cannabinoid receptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck Ribonucleoprotein Complex	Cytoplasm Mitochondrial Outer Membrane Plasma Membrane Integral Component Of Plasma Membrane Actin Cytoskeleton Growth Cone Integral Component Of Mitochondrial Membrane Membrane Raft Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Presynaptic Membrane
	Molecular Function	RNA Binding MRNA Binding Protein Binding	G Protein-coupled Receptor Activity Cannabinoid Receptor Activity Protein Binding Drug Binding Identical Protein Binding Voltage-gated Calcium Channel Activity Involved In Positive Regulation Of Presynaptic Cytosolic Calcium Levels
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Processing RNA Splicing Developmental Process	Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Spermatogenesis Axonal Fasciculation Aging Response To Nutrient Memory Positive Regulation Of Neuron Projection Development Negative Regulation Of Serotonin Secretion Regulation Of Metabolic Process Sensory Perception Of Pain Positive Regulation Of Fever Generation Negative Regulation Of Fatty Acid Beta-oxidation Regulation Of Synaptic Transmission, GABAergic Response To Lipopolysaccharide Negative Regulation Of Mast Cell Activation Negative Regulation Of Dopamine Secretion Response To Nicotine Cannabinoid Signaling Pathway Response To Cocaine Glucose Homeostasis Positive Regulation Of Apoptotic Process Response To Morphine Response To Ethanol Negative Regulation Of Action Potential Negative Regulation Of Blood Pressure Positive Regulation Of Blood Pressure Regulation Of Insulin Secretion Negative Regulation Of Nitric-oxide Synthase Activity Regulation Of Synaptic Transmission, Glutamatergic Maternal Process Involved In Female Pregnancy Regulation Of Feeding Behavior Regulation Of Penile Erection Retrograde Trans-synaptic Signaling By Endocannabinoid Trans-synaptic Signaling By Endocannabinoid, Modulating Synaptic Transmission Induction Of Synaptic Vesicle Exocytosis By Positive Regulation Of Presynaptic Cytosolic Calcium Ion Concentration
Pathways			Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events
Drugs			Dronabinol Nabilone Ricinoleic Acid SLV319 V24343 AVE-1625 Rimonabant Cannabidiol Propacetamol Otenabant Tetrahydrocannabivarin Medical Cannabis Nabiximols
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) QRS complex (12-leadsum) ( 27659466)	Depression in smokers ( 30219690) Gut microbiota (functional units) ( 27694959)
Interacting Genes		11 interacting genes: APP CNR1 CNRIP1 CTNNBL1 DISC1 FBXO25 NEDD4 NEDD4L RANBP9 SRPK1 SRPK2	8 interacting genes: GNA15 GNAI1 GNAI2 GNAI3 HCRTR1 MET NSRP1 SSTR5
Entrez ID		84081	1268
HPRD ID		08536	00259
Ensembl ID		ENSG00000126653	ENSG00000118432
Uniprot IDs		A0A024QZ33 B7ZL27 Q9H0G5	P21554 S5TLS4 V5KA96
PDB IDs			1LVQ 1LVR 2B0Y 2KOE 2MZ2 2MZ3 2MZA 5TGZ 5U09 5XR8 5XRA 6KPG 6KQI 6N4B
Enriched GO Terms of Interacting Partners?
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