CTTNBP2 and IMMP2L

Data Source:
BioGRID (affinity chromatography technology)

		CTTNBP2	IMMP2L
Description		cortactin binding protein 2	inner mitochondrial membrane peptidase subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Cortex Synaptic Vesicle Dendritic Spine Postsynaptic Actin Cytoskeleton Glutamatergic Synapse	Integral Component Of Membrane Mitochondrial Inner Membrane Peptidase Complex
	Molecular Function	Protein Binding SH3 Domain Binding	Serine-type Endopeptidase Activity Peptidase Activity
	Biological Process	Brain Development Regulation Of Modification Of Postsynaptic Actin Cytoskeleton	Ovarian Follicle Development Signal Peptide Processing Protein Processing Involved In Protein Targeting To Mitochondrion Superoxide Metabolic Process Cellular Response To DNA Damage Stimulus Spermatogenesis Brain Development Blood Circulation Respiratory Electron Transport Chain Ovulation Mitochondrial Respiratory Chain Complex Assembly Cerebellum Vasculature Development
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) General factor of neuroticism ( 30867560) Glaucoma ( 31959993 30054594) Glaucoma (primary open-angle) ( 29891935) Idiopathic osteonecrosis of the femoral head ( 28000841) Intraocular pressure ( 29617998 29785010 31959993 30054594) Positive urgency ( 30718321) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Subcortical volume (MOSTest) ( 32665545) Triglyceride levels ( 30108155) Type 2 diabetes ( 30054458 30297969) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Alzheimer's disease in APOE e4+ carriers ( 25778476) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Body size at age 10 ( 32376654) Cadmium levels ( 26025379) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive performance ( 19734545) Migraine ( 27322543) Night sleep phenotypes ( 27126917) Schizophrenia ( 28991256 25056061 29483656 30285260)
Interacting Genes		10 interacting genes: APPL1 ARNTL2 CTTN FAM86C1P HSF2BP INCA1 KRT14 MAGEA11 MEI4 PKNOX2	1 interacting genes: HNRNPD
Entrez ID		83992	83943
HPRD ID		09890	07297
Ensembl ID		ENSG00000077063	ENSG00000184903
Uniprot IDs		Q20BG9 Q8WZ74	A4D0S9 Q96T52
PDB IDs
Enriched GO Terms of Interacting Partners?
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