IMMP2L and CTTNBP2

Data Source:
BioGRID (affinity chromatography technology)

		IMMP2L	CTTNBP2
Description		inner mitochondrial membrane peptidase subunit 2	cortactin binding protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Mitochondrial Inner Membrane Peptidase Complex	Cell Cortex Synaptic Vesicle Dendritic Spine Postsynaptic Actin Cytoskeleton Glutamatergic Synapse
	Molecular Function	Serine-type Endopeptidase Activity Peptidase Activity	Protein Binding SH3 Domain Binding
	Biological Process	Ovarian Follicle Development Signal Peptide Processing Protein Processing Involved In Protein Targeting To Mitochondrion Superoxide Metabolic Process Cellular Response To DNA Damage Stimulus Spermatogenesis Brain Development Blood Circulation Respiratory Electron Transport Chain Ovulation Mitochondrial Respiratory Chain Complex Assembly Cerebellum Vasculature Development	Brain Development Regulation Of Modification Of Postsynaptic Actin Cytoskeleton
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease in APOE e4+ carriers ( 25778476) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Body size at age 10 ( 32376654) Cadmium levels ( 26025379) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive performance ( 19734545) Migraine ( 27322543) Night sleep phenotypes ( 27126917) Schizophrenia ( 28991256 25056061 29483656 30285260)	Brain morphology (MOSTest) ( 32665545) General factor of neuroticism ( 30867560) Glaucoma ( 31959993 30054594) Glaucoma (primary open-angle) ( 29891935) Idiopathic osteonecrosis of the femoral head ( 28000841) Intraocular pressure ( 29617998 29785010 31959993 30054594) Positive urgency ( 30718321) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Subcortical volume (MOSTest) ( 32665545) Triglyceride levels ( 30108155) Type 2 diabetes ( 30054458 30297969) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		1 interacting genes: HNRNPD	10 interacting genes: APPL1 ARNTL2 CTTN FAM86C1P HSF2BP INCA1 KRT14 MAGEA11 MEI4 PKNOX2
Entrez ID		83943	83992
HPRD ID		07297	09890
Ensembl ID		ENSG00000184903	ENSG00000077063
Uniprot IDs		A4D0S9 Q96T52	Q20BG9 Q8WZ74
PDB IDs
Enriched GO Terms of Interacting Partners?
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