HASPIN and ZNF594

Data Source:
BioGRID (affinity chromatography technology)

		HASPIN	ZNF594
Description		histone H3 associated protein kinase	zinc finger protein 594
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytoplasm Centrosome Spindle	Nucleus Nucleoplasm
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Histone Kinase Activity (H3-T3 Specific) Protein Serine Kinase Activity Protein Threonine Kinase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Metal Ion Binding
	Biological Process	Mitotic Cell Cycle Protein Phosphorylation Mitotic Sister Chromatid Cohesion Intracellular Signal Transduction Protein Localization To Chromosome, Centromeric Region Histone H3-T3 Phosphorylation Involved In Chromosome Passenger Complex Localization To Kinetochore	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs		5-iodotubercidin 3-(3-aminophenyl)-N-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-amine H-89 (2S)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-ol
Diseases
GWAS
Interacting Genes		5 interacting genes: AURKB H3C1 HSF2BP MDFI PDS5B	1 interacting genes: GOLGA2
Entrez ID		83903	84622
HPRD ID		17083	15867
Ensembl ID		ENSG00000177602	ENSG00000180626
Uniprot IDs		A0PJ70 Q8TF76	Q6ZNC6 Q96JF6
PDB IDs		2VUW 2WB8 3DLZ 3E7V 3F2N 3FMD 3IQ7 4OUC 4QTC 5HTB 5HTC 6G34 6G35 6G36 6G37 6G38 6G39 6G3A 6Z56 6Z57 6Z58 6Z59 6Z5A 6Z5B 6Z5C 6Z5D 6Z5E
Enriched GO Terms of Interacting Partners?
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