TFAP2D and SSC4D

Data Source:
BioGRID (two hybrid)

		TFAP2D	SSC4D
Description		transcription factor AP-2 delta	scavenger receptor cysteine rich family member with 4 domains
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex	Extracellular Region Membrane
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding	Scavenger Receptor Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Population Proliferation Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development Inferior Colliculus Development	Endocytosis
Pathways		Negative regulation of activity of TFAP2 (AP-2) family transcription factors Negative regulation of activity of TFAP2 (AP-2) family transcription factors Activation of the TFAP2 (AP-2) family of transcription factors
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Body mass index ( 29273807) Breast size ( 22747683) Endometriosis or endometrial cancer (pleiotropy) ( 29608257) Fruit consumption ( 32066663) Hand grip strength ( 29691431) Overweight status ( 25133637) Parahippocampal gyrus volume ( 31530798) Refractive error ( 32231278) Response to citalopram or escitalopram in depression ( 27622933) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Subcutaneous adipose tissue ( 29178545) Systolic blood pressure ( 28135244) Western dietary pattern ( 28644415)
Interacting Genes		64 interacting genes: ADAM12 ADAMTSL4 AGR2 AKAP8L BAG4 CAMK2A CARD10 CDPF1 CEP76 CNFN CSNK2B CYSRT1 FAM166B FAM168A GUCD1 GYS1 HOXD12 IKZF3 INCA1 KLHL20 KPRP KRT31 KRT34 KRTAP1-1 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP11-1 KRTAP12-3 KRTAP15-1 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP9-2 KRTAP9-3 MLH1 OIP5 PITX1 PLEKHG4 PRR22 PSMB4 RAD54L2 SIVA1 SLAIN1 SPRY1 SSC4D TEPSIN TEX37 TLE5 TNS2 TRAF1 TRIM42 TSC1 USP54 VPS37C ZBTB32 ZMYND12	32 interacting genes: ATXN7L2 CATSPER1 CNNM3 COL8A1 CREB5 CYSRT1 ENKD1 GNE HAPLN2 HOXA1 HSD3B7 KRTAP10-8 KRTAP12-4 KRTAP13-2 KRTAP26-1 KRTAP3-3 MGAT5B NFKBID PCSK5 PLEKHN1 PLSCR4 PRKAB2 PTPMT1 RECK RHOU STK16 TEKT5 TFAP2D TLE5 TRIP13 TROAP VASN
Entrez ID		83741	136853
HPRD ID		11627	06364
Ensembl ID		ENSG00000008197	ENSG00000146700
Uniprot IDs		Q7Z6R9	Q8WTU2
PDB IDs
Enriched GO Terms of Interacting Partners?
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