CALN1 and SLPI

Data Source:
BioGRID (two hybrid)

		CALN1	SLPI
Description		calneuron 1	secretory leukocyte peptidase inhibitor
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm	Extracellular Region Extracellular Space Golgi Apparatus Specific Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding	DNA Binding MRNA Binding Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding Enzyme Binding
	Biological Process		Immune Response Negative Regulation Of Endopeptidase Activity Antibacterial Humoral Response Negative Regulation Of Protein Binding Response To Lipopolysaccharide Modulation Of Process Of Other Organism Neutrophil Degranulation Negative Regulation Of Viral Genome Replication Innate Immune Response
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Corneal astigmatism ( 29422769) Emotional recognition ( 32366958) General cognitive ability ( 29844566) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Lifetime average cigarettes per day in chronic obstructive pulmonary disease ( 21685187) Logical memory (delayed recall) in normal cognition ( 29274321) Refractive error ( 32231278) Schizophrenia ( 28991256 30285260) Sedentary behaviour duration ( 30531941) Triglyceride levels ( 32203549 32154731)	Bipolar disorder ( 31043756) Blood protein levels ( 30072576 28240269) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Malaria ( 31844061)
Interacting Genes		9 interacting genes: DNAJC30 FATE1 LIME1 MAL PLP1 SEC22A SLPI SYCE1L USE1	25 interacting genes: CALN1 CIB3 CTSB CTSL CTSS EFEMP1 ELANE FAM9B GRN HOXA1 KLK3 LAT MAPK8IP2 MICOS10-NBL1 MKRN3 NBL1 NTAQ1 PIH1D2 PLSCR1 PRSS2 SGTA SGTB SMIM14 UBQLN1 UBQLN2
Entrez ID		83698	6590
HPRD ID		06209	00121
Ensembl ID		ENSG00000183166	ENSG00000124107
Uniprot IDs		A4D1Z1 Q9BXU9	P03973
PDB IDs			2Z7F 4DOQ
Enriched GO Terms of Interacting Partners?
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