C11orf68 and KCNE3

Data Source:
BioGRID (two hybrid)

		C11orf68	KCNE3
Description		chromosome 11 open reading frame 68	potassium voltage-gated channel subfamily E regulatory subunit 3
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GO Annotations	Cellular Component		Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex Dendrite Vesicle Neuronal Cell Body Membrane Perikaryon Membrane Raft
	Molecular Function	RNA Binding Protein Binding	Delayed Rectifier Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity Ion Channel Binding Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization
	Biological Process		Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Regulation Of Heart Rate By Cardiac Conduction Potassium Ion Export Across Plasma Membrane Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Positive Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Potassium Ion Export Across Plasma Membrane Negative Regulation Of Voltage-gated Potassium Channel Activity Negative Regulation Of Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential
Pathways			Phase 3 - rapid repolarisation Phase 2 - plateau phase
Drugs			Enflurane Promethazine Miconazole
Diseases			Brugada syndrome (BRS)
GWAS		Acne (severe) ( 24927181) Asthma ( 31959851)	Corneal astigmatism ( 22144915) Neuritic plaque ( 31497858)
Interacting Genes		14 interacting genes: CSDE1 EIF4H KCNE3 KLF15 MEOX2 MTCL1 NONO PHETA1 REL SDCBP SH3GL3 TRAPPC2L ZNF341 ZNF512B	10 interacting genes: C11orf68 EEF1A1 GAPDH GOLM1 KIF5A LRIF1 POLA2 QARS1 RASSF1 SLC44A1
Entrez ID		83638	10008
HPRD ID		12553	07256
Ensembl ID		ENSG00000175573	ENSG00000175538
Uniprot IDs		Q9H3H3	Q6IAE6 Q9Y6H6
PDB IDs		1ZTP 2Q4K	2NDJ 6V00 6V01
Enriched GO Terms of Interacting Partners?
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