EMC6 and PDZK1IP1

Data Source:
BioGRID (two hybrid)

		EMC6	PDZK1IP1
Description		ER membrane protein complex subunit 6	PDZK1 interacting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane EMC Complex Integral Component Of Omegasome Membrane	Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding Membrane Insertase Activity	Protein Binding
	Biological Process	Autophagosome Assembly Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways
Drugs
Diseases
GWAS			Clozapine-induced agranulocytosis ( 25187353)
Interacting Genes		17 interacting genes: AQP6 AQP9 CD79A CREB3 EBP ERGIC3 FAM209A MFSD14B MMD MUC1 PDZK1IP1 SLC10A6 SLC39A2 SLC7A1 TLCD4 TMEM14B TMEM237	77 interacting genes: AGR3 AIG1 APOA2 APOD AQP2 AQP6 ARL13B ASGR1 C14orf180 C2CD2L CD81 CES1 CLDN19 COPS6 CYB5B CYBC1 EMC6 ERG28 FAM3C FCER1G GALNT15 GAST GIMAP5 GRM2 GYPA HMOX1 ICMT IGFBP5 JAGN1 LEPROTL1 LHFPL5 MIP MYADM MYADML2 NSG1 NUMB PDZK1 PEX16 PGAP2 PLP2 PLPP4 PLPP6 PMP22 RPRM RTP2 SDCBP SFTPC SFXN2 SLC22A1 SLC22A2 SLC35B1 SLC35B4 STRIT1 STX12 THBD TMEM101 TMEM107 TMEM109 TMEM11 TMEM140 TMEM14A TMEM14B TMEM14C TMEM203 TMEM39B TMEM65 TMEM86A TMEM97 TNFRSF10C TRARG1 TRIM54 TSPO2 UPK1B UTP14A VAMP3 YIPF6 ZDHHC17
Entrez ID		83460	10158
HPRD ID		14529	06211
Ensembl ID		ENSG00000127774	ENSG00000162366
Uniprot IDs		Q9BV81	Q13113
PDB IDs		6WW7 6Z3W
Enriched GO Terms of Interacting Partners?
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