TMEM187 and SPAG4

Data Source:
BioGRID (two hybrid)

		TMEM187	SPAG4
Description		transmembrane protein 187	sperm associated antigen 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Transport Vesicle	Nuclear Envelope Nuclear Inner Membrane Cytoplasm Cytoskeleton Integral Component Of Membrane Motile Cilium Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	Molecular_function Protein Binding	Structural Molecule Activity Protein Binding Protein-membrane Adaptor Activity
	Biological Process	Biological_process	Nuclear Envelope Organization Spermatogenesis Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Celiac disease ( 22057235) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus ( 26663301 26502338)	Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		15 interacting genes: ADRB2 ARL13B CD79A CGRRF1 CISD2 COMT FAM210B GORAB LEUTX MUC1 PGRMC2 SAR1A SPAG4 TAS2R5 TMEM14B	24 interacting genes: ABHD16A ASGR1 BMP10 CSGALNACT1 ERMP1 GOSR2 IGFBP5 MS4A13 NRM ODF1 PAXIP1 PGA4 PLN PTPN9 RUSF1 SCAMP4 SCD SEC22A SUN5 TMEM187 TMEM60 TNMD TRARG1 TSPO2
Entrez ID		8269	6676
HPRD ID		02086	04330
Ensembl ID		ENSG00000177854	ENSG00000061656
Uniprot IDs		Q14656	Q9NPE6
PDB IDs
Enriched GO Terms of Interacting Partners?
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