UBL4A and PER2

Data Source:
BioGRID (two hybrid)

		UBL4A	PER2
Description		ubiquitin like 4A	period circadian regulator 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane BAT3 Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Ubiquitin-like Protein Transferase Activity Chaperone Binding	Transcription Regulatory Region Sequence-specific DNA Binding Transcription Corepressor Binding Transcription Coactivator Activity Protein Binding
	Biological Process	Cellular Protein Modification Process Protein Phosphopantetheinylation Tail-anchored Membrane Protein Insertion Into ER Membrane	Negative Regulation Of Transcription By RNA Polymerase II Response To Ischemia Glycogen Biosynthetic Process Gluconeogenesis Fatty Acid Metabolic Process Circadian Rhythm Regulation Of Vasoconstriction Lactate Biosynthetic Process Negative Regulation Of Protein Ubiquitination Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Neurogenesis Regulation Of Insulin Secretion White Fat Cell Differentiation Regulation Of Cell Cycle Regulation Of Glutamate Uptake Involved In Transmission Of Nerve Impulse Negative Regulation Of Fat Cell Proliferation Histone H3 Deacetylation Circadian Regulation Of Translation Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of Transcription Regulatory Region DNA Binding
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Circadian Clock
Drugs
Diseases			Familial advanced sleep phase syndrome
GWAS		Neutrophil count ( 32888494)	Chronotype ( 26955885 30696823 27494321) Morning vs. evening chronotype ( 26955885 26835600 27494321)
Interacting Genes		14 interacting genes: AMFR APP CDCA7L ERP27 MEOX2 PER2 RNF126 S100P SEC61B SGTA SGTB TRAF4 TRIM54 USP13	25 interacting genes: BHLHE41 BTRC CLOCK CRY1 CRY2 CSNK1D CSNK1E CSNK2B DELEC1 ELOA LENG8 LMO4 MDM2 MLH1 PER1 PER3 RORC TIMELESS TP53 TPT1 TPTEP2-CSNK1E UBE2D1 UBE2D2 UBE2D3 UBL4A
Entrez ID		8266	8864
HPRD ID		02417	04575
Ensembl ID		ENSG00000102178	ENSG00000132326
Uniprot IDs		P11441	O15055
PDB IDs		2DZI 4WWR 4X86	6OF7
Enriched GO Terms of Interacting Partners?
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