UBL4A and AMFR

Data Source:
BioGRID (affinity chromatography technology, enzymatic study, affinity chromatography technology)

		UBL4A	AMFR
Description		ubiquitin like 4A	autocrine motility factor receptor
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane BAT3 Complex	Ubiquitin Ligase Complex Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Dendrite Growth Cone Protein-containing Complex Derlin-1 Retrotranslocation Complex Neuronal Cell Body Endoplasmic Reticulum Quality Control Compartment Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Ubiquitin-like Protein Transferase Activity Chaperone Binding	Ubiquitin-protein Transferase Activity Protein Binding Protein-macromolecule Adaptor Activity Ubiquitin-ubiquitin Ligase Activity Signaling Receptor Activity Identical Protein Binding Ubiquitin Binding Metal Ion Binding Chaperone Binding Ubiquitin Protein Ligase Activity BAT3 Complex Binding Ubiquitin-specific Protease Binding
	Biological Process	Cellular Protein Modification Process Protein Phosphopantetheinylation Tail-anchored Membrane Protein Insertion Into ER Membrane	Protein Polyubiquitination Protein Folding Ubiquitin-dependent Protein Catabolic Process Signal Transduction Aging Learning Or Memory Wnt Signaling Pathway Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Protein Binding Protein Autoubiquitination Protein K48-linked Ubiquitination Negative Regulation Of Canonical Wnt Signaling Pathway Endoplasmic Reticulum Mannose Trimming Regulation Of SREBP Signaling Pathway
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	N-glycan trimming in the ER and Calnexin/Calreticulin cycle ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS		Neutrophil count ( 32888494)	Apolipoprotein A1 levels ( 32203549) Breast cancer ( 29059683)
Interacting Genes		14 interacting genes: AMFR APP CDCA7L ERP27 MEOX2 PER2 RNF126 S100P SEC61B SGTA SGTB TRAF4 TRIM54 USP13	28 interacting genes: BAG6 CRMP1 CYP2E1 DERL1 DHFR GPI HERPUD1 HTT KPNB1 MGRN1 SOD1 TOM1L1 TRIM25 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2G1 UBE2G2 UBE2K UBE2N UBE2T UBE2W UBL4A UFD1 USP13 VCP
Entrez ID		8266	267
HPRD ID		02417	09130
Ensembl ID		ENSG00000102178	ENSG00000159461
Uniprot IDs		P11441	A0A024R6R5 Q9UKV5
PDB IDs		2DZI 4WWR 4X86	2EJS 2LVN 2LVO 2LVP 2LVQ 2LXH 2LXP 3FSH 3H8K 3TIW 4G3O 4LAD
Enriched GO Terms of Interacting Partners?
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