UBL4A and MYH10

Data Source:
BioGRID (proximity labelling technology)

		UBL4A	MYH10
Description		ubiquitin like 4A	myosin heavy chain 10
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane BAT3 Complex	Stress Fiber Nucleus Cytoplasm Cytosol Polysome Cell Cortex Myosin Complex Myosin II Complex Lamellipodium Midbody Cleavage Furrow Actomyosin Extracellular Exosome Myosin II Filament
	Molecular Function	Protein Binding Ubiquitin-like Protein Transferase Activity Chaperone Binding	Microfilament Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding ATPase Activity Actin-dependent ATPase Activity RNA Stem-loop Binding ADP Binding MRNA 5'-UTR Binding Actin Filament Binding
	Biological Process	Cellular Protein Modification Process Protein Phosphopantetheinylation Tail-anchored Membrane Protein Insertion Into ER Membrane	Mitotic Cytokinesis Cell Adhesion Regulation Of Cell Shape Actin Filament-based Movement Actomyosin Structure Organization Positive Regulation Of Protein Secretion Modification Of Postsynaptic Actin Cytoskeleton
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs
Drugs
Diseases
GWAS		Neutrophil count ( 32888494)	Type 2 diabetes ( 30130595)
Interacting Genes		14 interacting genes: AMFR APP CDCA7L ERP27 MEOX2 PER2 RNF126 S100P SEC61B SGTA SGTB TRAF4 TRIM54 USP13	11 interacting genes: APC BCAP31 DUX4 ECPAS MYH9 PBX1 PTEN S100A4 YWHAE YWHAG ZNF512B
Entrez ID		8266	4628
HPRD ID		02417	01178
Ensembl ID		ENSG00000102178	ENSG00000133026
Uniprot IDs		P11441	G1UI33 P35580
PDB IDs		2DZI 4WWR 4X86	4PD3
Enriched GO Terms of Interacting Partners?
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