ZRSR2 and U2AF1

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		ZRSR2	U2AF1
Description		zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2	U2 small nuclear RNA auxiliary factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex U2AF Complex	Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck Catalytic Step 2 Spliceosome U2AF Complex
	Molecular Function	Protein Binding Pre-mRNA 3'-splice Site Binding Identical Protein Binding Metal Ion Binding	RNA Binding Protein Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding
	Biological Process	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing
Pathways		mRNA Splicing - Minor Pathway	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS			Blood and toenail selenium levels ( 25343990)
Interacting Genes		19 interacting genes: APP CCNL1 CLK2 DVL3 KHDC4 LUC7L2 REP15 SDCBP2 SRPK2 SRRM4 SRSF1 SRSF2 SRSF5 SSX2IP TEPSIN TNFAIP8L1 U2AF1 U2AF2 ZRSR2P1	51 interacting genes: AP1B1 AP2B1 CARNMT1 CHERP CIR1 CLK2 DHX38 EFHC2 EPB41 FRA10AC1 HINFP HNRNPK HNRNPM IL7R JMJD6 KRT1 KRT75 MAP1B MEOX2 MFAP1 MLH1 NDN NKAP NXF1 PABPC1 PRPF19 PRPF38A PRPF4 PRPF40A PTEN RBM10 RNPS1 RP9 SF3A3 SF3B2 SNRNP35 SNRPD1 SRPK1 SRRM4 SRSF1 SRSF2 SRSF3 SUV39H1 TOE1 TRA2B U2AF2 VEGFA ZCCHC10 ZNF417 ZRANB2 ZRSR2
Entrez ID		8233	7307
HPRD ID		02068	01871
Ensembl ID		ENSG00000169249	ENSG00000160201
Uniprot IDs		Q15696	P0DN76 Q01081 Q7Z780
PDB IDs			1JMT
Enriched GO Terms of Interacting Partners?
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