ESS2 and PFDN1

		ESS2	PFDN1
Description		ess-2 splicing factor homolog	prefoldin subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Catalytic Step 2 Spliceosome	Cytoplasm Prefoldin Complex
	Molecular Function	Molecular_function Protein Binding	Amyloid-beta Binding Protein Binding Protein Folding Chaperone Unfolded Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Nervous System Development	Protein Folding Negative Regulation Of Amyloid Fibril Formation
Pathways			Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS			Alzheimer's disease ( 28183528) Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Reaction time ( 29844566)
Interacting Genes		18 interacting genes: ARMC7 CCDC57 CDK5RAP3 CRP DGCR6 DHX16 EXOC8 FRA10AC1 LYST OIP5 PFDN1 QARS1 RACK1 RBM4 SMARCD1 TTC14 VIM WNK2	54 interacting genes: ACTA1 ACTB ALB BRK1 CCDC85A CEP126 CHGA DCTN1 DEFA1 DMAP1 EDRF1 EIF3C EIF4A2 EOMES ESS2 EXT2 EZH2 FAM20C GET3 GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 YEATS4 ZNF235
Entrez ID		8220	5201
HPRD ID		03452	05357
Ensembl ID		ENSG00000100056	ENSG00000113068
Uniprot IDs		F8WEF8 Q96DF8	O60925
PDB IDs			6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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