DGCR6 and DNPEP

Data Source:
BioGRID (two hybrid)

		DGCR6	DNPEP
Description		DiGeorge syndrome critical region gene 6	aspartyl aminopeptidase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Extracellular Matrix	Nucleus Cytoplasm Cytosol Blood Microparticle
	Molecular Function	Molecular_function Protein Binding	Aminopeptidase Activity Protein Binding Metallopeptidase Activity Zinc Ion Binding Identical Protein Binding
	Biological Process	Cell Adhesion Animal Organ Morphogenesis	Proteolysis Peptide Metabolic Process
Pathways
Drugs			Glutamic acid
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Metabolite levels ( 23823483) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259)	Height ( 31562340) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		66 interacting genes: ADAMTSL4 AGTRAP AKAP8L APP ARNT2 C1orf94 C3orf62 CBLL1 CBY2 CCDC33 CEP126 CTBP1 DEUP1 DLGAP2 DLX2 DNPEP DOCK8 EFEMP2 EFHC2 ENKD1 ESS2 FBF1 FH GOLGA2 GSE1 HGS HOMEZ IHO1 IKZF3 INIP KLHL12 KRTAP12-2 LZTS2 MBIP MEIS2 MEOX2 MIA2 MID2 MIPOL1 NAB2 NECAB2 NOTCH2NLA NQO2 NUP54 NUP62 PDLIM7 PRDM14 RABGEF1 REL RFX6 RIMBP3 SPRY2 SS18L1 TCF12 TCF4 TFIP11 TLE5 TRAF1 TRAF2 TRIM27 TUBGCP4 VCP ZBED1 ZC4H2 ZNF398 ZNF446	8 interacting genes: ADAMTSL4 AGT DGCR6 LNX1 MDFI MPP1 PAK5 SAT1
Entrez ID		8214	23549
HPRD ID		03177	09924
Ensembl ID		ENSG00000183628	ENSG00000123992
Uniprot IDs		Q14129 X5D7D2	A0A024R443 B7Z7F0 E5RIA4 E7ETB3 Q9ULA0
PDB IDs			4DYO
Enriched GO Terms of Interacting Partners?
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