ASF1A and PAFAH1B2

Data Source:
HPRD (two hybrid)

		ASF1A	PAFAH1B2
Description		anti-silencing function 1A histone chaperone	platelet activating factor acetylhydrolase 1b catalytic subunit 2
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Protein-containing Complex	Fibrillar Center Extracellular Region Nucleolus Cytoplasm Cytosol Plasma Membrane 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Chromatin Binding Protein Binding Histone Binding	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity
	Biological Process	Osteoblast Differentiation DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Negative Regulation Of Chromatin Silencing Muscle Cell Differentiation	Lipid Metabolic Process Spermatogenesis Brain Development Lipid Catabolic Process Positive Regulation Of Macroautophagy Neutrophil Degranulation
Pathways		Formation of Senescence-Associated Heterochromatin Foci (SAHF)	Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494) Multiple sclerosis ( 31604244) QT interval ( 19305408)	Adult body size ( 32376654) Blood protein levels ( 28240269 23696881) HDL cholesterol ( 24507774) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Protein quantitative trait loci ( 18464913) Refractive error ( 32231278) Systolic blood pressure ( 30578418)
Interacting Genes		35 interacting genes: ASF1B CDAN1 CHAF1A CHAF1B CHEK2 H3-3A H3-4 H3C3 H3C6 H4-16 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HIRA HTATIP2 MCM2 NASP PAFAH1B2 PRR3 ST13 TAF1 TLK1 TLK2 VPS28 ZDHHC17	19 interacting genes: ACIN1 ASF1A CCT3 CLVS2 CRK PAFAH1B1 PAFAH1B3 PINX1 PPP1R12C PRKN REXO1 RPLP0 SLA SNUPN STAT3 TIMM50 TRIM55 TRIM63 ZFP36L1
Entrez ID		25842	5049
HPRD ID		16459	03940
Ensembl ID		ENSG00000111875	ENSG00000168092
Uniprot IDs		Q9Y294	P68402 V9HW44
PDB IDs		1TEY 2I32 2IIJ 2IO5 3AAD 5C3I 6F0F 6F0G 6F0H	1VYH
Enriched GO Terms of Interacting Partners?
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