CAMLG and TNFRSF13B

Data Source:
HPRD (in vivo, two hybrid)

		CAMLG	TNFRSF13B
Description		calcium modulating ligand	TNF receptor superfamily member 13B
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Cell Adhesion Molecule Binding	Protein Binding Signaling Receptor Activity
	Biological Process	Defense Response Signal Transduction Viral Process Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization	B Cell Homeostasis Hematopoietic Progenitor Cell Differentiation Adaptive Immune Response Cell Surface Receptor Signaling Pathway Negative Regulation Of B Cell Proliferation Tumor Necrosis Factor-mediated Signaling Pathway
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	TNFs bind their physiological receptors
Drugs		Cyclosporine
Diseases			Common variable immunodeficiency (CVID), including the following four diseases: Inducible T Cell costimulator (ICOS) defect; TACI defect; CD19 defect; BAFFR defect
GWAS		Height ( 18391951)	Albumin-globulin ratio ( 29403010) Apolipoprotein A1 levels ( 32203549) Diabetic retinopathy ( 21441570) Granulocyte percentage of myeloid white cells ( 27863252) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Hematological and biochemical traits ( 20139978) Hematology traits ( 23303382) IgG levels ( 22673310) Immunoglobulin light chain (AL) amyloidosis ( 28025584) Immunoglobulin measurement (zinc sulfate turbidity test) ( 29403010) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monoclonal gammopathy of undetermined significance ( 30737484) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Multiple myeloma ( 32569378 26007630 23955597) Multiple myeloma and monoclonal gammopathy ( 26007630) Neutrophil percentage of white cells ( 32888494) Non-albumin protein levels ( 22558069 29403010) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Serum albumin level ( 29403010) Serum total protein level ( 23022100 29403010) Sodium levels ( 29403010) Tonsillectomy ( 27182965 28928442) White blood cell count ( 32888494)
Interacting Genes		22 interacting genes: ADIPOQ AGR2 EGFR ETNK1 F11R GET1 GET3 HSP90B1 KCNA2 KCNE4 LAT LCN2 OCIAD1 PBXIP1 PGRMC1 PKHD1 PPIB RPN1 TMEM31 TNFRSF13B TXNDC12 VWC2	7 interacting genes: CAMLG SGTA TNFSF13 TNFSF13B TRAF2 TRAF5 TRAF6
Entrez ID		819	23495
HPRD ID		03073	05365
Ensembl ID		ENSG00000164615	ENSG00000240505
Uniprot IDs		P49069	O14836 Q4ACX1
PDB IDs		6SO5	1XU1 1XUT
Enriched GO Terms of Interacting Partners?
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