ARPC5L and ARPC4

Data Source:
BioGRID (two hybrid, proximity labelling technology)
HPRD (two hybrid)

		ARPC5L	ARPC4
Description		actin related protein 2/3 complex subunit 5 like	actin related protein 2/3 complex subunit 4
Image
GO Annotations	Cellular Component	Cytoplasm Arp2/3 Protein Complex Focal Adhesion Extracellular Exosome Glutamatergic Synapse	Nucleus Cytosol Arp2/3 Protein Complex Site Of Double-strand Break Cell Projection Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding Actin Filament Binding	Structural Constituent Of Cytoskeleton Protein Binding Enzyme Binding Protein-macromolecule Adaptor Activity Actin Filament Binding
	Biological Process	Biological_process Cell Migration Arp2/3 Complex-mediated Actin Nucleation	Actin Filament Polymerization Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Actin Nucleation Ephrin Receptor Signaling Pathway Membrane Organization
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs			N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS
Interacting Genes		2 interacting genes: ARPC4 GADD45G	13 interacting genes: ACTR2 ACTR3 ARPC1B ARPC2 ARPC3 ARPC5 ARPC5L CLK1 METTL21A NELFCD PNMA5 RNF130 WASL
Entrez ID		81873	10093
HPRD ID		12490	10368
Ensembl ID		ENSG00000136950	ENSG00000241553
Uniprot IDs		A0A024R897 B3KPC7 Q9BPX5	P59998
PDB IDs		6YW6	6UHC 6YW6 6YW7
Enriched GO Terms of Interacting Partners?
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