SPACA1 and AGPAT4

Data Source:
BioGRID (two hybrid)

		SPACA1	AGPAT4
Description		sperm acrosome associated 1	1-acylglycerol-3-phosphate O-acyltransferase 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Inner Acrosomal Membrane Acrosomal Membrane Integral Component Of Membrane	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Integral Component Of Membrane
	Molecular Function	Protein Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity Protein Binding Transferase Activity, Transferring Acyl Groups
	Biological Process	Acrosome Assembly	Phosphatidic Acid Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Biosynthetic Process
Pathways			Synthesis of PA
Drugs
Diseases
GWAS		Echocardiographic traits ( 17903301) Left superior temporal gyrus thickness (schizophrenia interaction) ( 26249676)	Anxiety in major depressive disorder ( 24047446) Diastolic blood pressure ( 30224653) Energy expenditure (24h) ( 28476931) Fear of pain ( 28701861) Lipoprotein (a) - cholesterol levels ( 25575512) Lipoprotein (a) levels ( 26377243) Metabolite levels ( 23823483)
Interacting Genes		25 interacting genes: AGPAT4 ATP6V0B ATP6V0C BNIP3 CACNG7 CD72 CLDN19 CTXN3 EMP1 EMP3 GIMAP5 LSMEM2 NRSN1 NSG1 PLN PMP22 RPRM SERP2 SERTM1 SGCG SMAGP SMIM3 THSD7B TMEM140 TMEM47	28 interacting genes: AQP12B AQP6 CNR2 CREB3L1 ERGIC3 FCGR2A FCRL3 FFAR2 GPR101 HSD17B11 HSD17B13 JAGN1 LEPROTL1 LEUTX LRRC25 MFF MFSD14B MGST3 REEP4 REL RETREG3 SCN3B SLC35C2 SLC7A8 SPACA1 TMEM14B TMEM31 TMX2
Entrez ID		81833	56895
HPRD ID		15419	12437
Ensembl ID		ENSG00000118434	ENSG00000026652
Uniprot IDs		Q9HBV2	Q9NRZ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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