SF3A2 and RETN

Data Source:
HPRD (in vitro)

		SF3A2	RETN
Description		splicing factor 3a subunit 2	resistin
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2 SnRNP Nuclear Speck U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Extracellular Region Extracellular Space Nucleus Azurophil Granule Lumen Specific Granule Lumen Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding	Hormone Activity Protein Binding
	Biological Process	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing Positive Regulation Of Neuron Projection Development U2-type Prespliceosome Assembly	Signal Transduction Aging Biological_process Response To Mechanical Stimulus Response To Insulin Neutrophil Degranulation Fat Cell Differentiation Positive Regulation Of Synaptic Transmission Negative Regulation Of Feeding Behavior Positive Regulation Of Progesterone Secretion
Pathways		mRNA Splicing - Major Pathway	Neutrophil degranulation FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
Drugs		Copper
Diseases
GWAS		Adult body size ( 32376654) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Myocardial infarction ( 24916648) Pulse pressure ( 26390057)	Blood protein levels ( 30072576 29875488) Menarche (age at onset) ( 25231870) Resistin levels ( 27664181 24123702 22843503)
Interacting Genes		20 interacting genes: APBB1 ASPH BAIAP2 BEND2 CDC42 GRB2 HTATSF1 LIN54 NCK2 OSTF1 PRPF40A RETN SF3A1 SH3RF1 SMURF2 TCERG1 TFG TRIP10 VEZF1 YY1	3 interacting genes: A2M GPR25 SF3A2
Entrez ID		8175	56729
HPRD ID		02877	05714
Ensembl ID		ENSG00000104897	ENSG00000104918
Uniprot IDs		Q05DF2 Q15428	Q9HD89
PDB IDs		5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6QX9 6Y53 6Y5Q	1LV6
Enriched GO Terms of Interacting Partners?
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