TSSK3 and UROD

Data Source:
BioGRID (two hybrid)

		TSSK3	UROD
Description		testis specific serine kinase 3	uroporphyrinogen decarboxylase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Cytosol
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Uroporphyrinogen Decarboxylase Activity Protein Binding
	Biological Process	Protein Phosphorylation Multicellular Organism Development Spermatogenesis Cell Differentiation Intracellular Signal Transduction	Protoporphyrinogen IX Biosynthetic Process Heme Biosynthetic Process
Pathways			Heme biosynthesis
Drugs			Coproporphyrin I Coproporphyrinogen III
Diseases			Hepatic porphyria, including: Porphyria Cutanea Tarda (PCT); VHepatoerythropoietic porphyria; Acute Intermittent Porphyria (AIP); Variegate porphyria (VP); ALA-dehydratase deficiency porphyria (ALADP); Hereditary Coproporphyria (HCP)
GWAS		Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		67 interacting genes: ADAMTSL4 ARID5A ATP23 C15orf48 C2CD6 C9orf24 CCDC130 CENPN DDIT4L DRG2 ECSIT EFHC2 EYA2 FUT9 GOLGA2 GP2 IKZF3 INCA1 KRT75 KRTAP13-2 KRTAP13-3 LBX1 LHX3 LMO2 LNX1 LZTS2 MBD3L1 MEI4 MRPL28 MSX2 MYOG MYOZ3 NFKBID NME4 OIP5 PBX4 PJA1 PLEKHG4 PPP1R16A PRDM6 RBBP4 RBCK1 REL RIN3 RUSC1 SHISA6 SLAIN1 SMAD4 STAT5B SYNGAP1 TCF4 TCP10L TEPSIN TGM7 TLE5 TRIM35 TRIM50 TRIM54 TRIM9 TRIP6 UROD USP54 VGLL1 VPS52 YPEL3 ZBTB25 ZMYND12	10 interacting genes: CHD3 EGFR FAF1 FBXO7 HMGXB4 LRATD2 PHKA2 PILRA TSSK3 VIM
Entrez ID		81629	7389
HPRD ID		09635	01441
Ensembl ID		ENSG00000162526	ENSG00000126088
Uniprot IDs		Q96PN8	P06132
PDB IDs			1JPH 1JPI 1JPK 1R3Q 1R3R 1R3S 1R3T 1R3V 1R3W 1R3Y 1URO 2Q6Z 2Q71 3GVQ 3GVR 3GVV 3GVW 3GW0 3GW3
Enriched GO Terms of Interacting Partners?
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