UROD and PILRA

Data Source:
BioGRID (two hybrid)

		UROD	PILRA
Description		uroporphyrinogen decarboxylase	paired immunoglobin like type 2 receptor alpha
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GO Annotations	Cellular Component	Nucleoplasm Cytosol	Plasma Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Uroporphyrinogen Decarboxylase Activity Protein Binding	Protein Binding MHC Class I Protein Binding
	Biological Process	Protoporphyrinogen IX Biosynthetic Process Heme Biosynthetic Process	Signal Transduction Viral Process Regulation Of Immune Response
Pathways		Heme biosynthesis	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		Coproporphyrin I Coproporphyrinogen III
Diseases		Hepatic porphyria, including: Porphyria Cutanea Tarda (PCT); VHepatoerythropoietic porphyria; Acute Intermittent Porphyria (AIP); Variegate porphyria (VP); ALA-dehydratase deficiency porphyria (ALADP); Hereditary Coproporphyria (HCP)
GWAS			Advanced age-related macular degeneration ( 26691988) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Red cell distribution width ( 32888494) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		10 interacting genes: CHD3 EGFR FAF1 FBXO7 HMGXB4 LRATD2 PHKA2 PILRA TSSK3 VIM	10 interacting genes: DNPH1 FAM114A2 FCAR PAICS PFDN5 PTPN11 PTPN6 SORBS1 TOM1 UROD
Entrez ID		7389	29992
HPRD ID		01441	05631
Ensembl ID		ENSG00000126088	ENSG00000085514
Uniprot IDs		P06132	Q9UKJ1
PDB IDs		1JPH 1JPI 1JPK 1R3Q 1R3R 1R3S 1R3T 1R3V 1R3W 1R3Y 1URO 2Q6Z 2Q71 3GVQ 3GVR 3GVV 3GVW 3GW0 3GW3	3WUZ 3WV0 4NFB 5XO2 5XOF
Enriched GO Terms of Interacting Partners?
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