TRIM11 and MED15

Data Source:
HPRD (in vivo)

		TRIM11	MED15
Description		tripartite motif containing 11	mediator complex subunit 15
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Nucleoplasm Cytoplasm Membrane Mediator Complex
	Molecular Function	Protein Binding Transcription Factor Binding Zinc Ion Binding Protein Domain Specific Binding Ubiquitin Protein Ligase Activity	Transcription Coregulator Activity Protein Binding
	Biological Process	Regulation Of Gene Expression Protein Ubiquitination Negative Regulation Of Viral Transcription Innate Immune Response Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Viral Entry Into Host Cell Negative Regulation Of Neurogenesis Defense Response To Virus Negative Regulation Of Viral Release From Host Cell	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Hip circumference (psychosocial stress interaction) ( 25271088) Non-Richardson's syndrome vs Richardson's syndrome in progressive supranuclear palsy ( 30066433)	Lung function (FEV1/FVC) ( 30061609)
Interacting Genes		7 interacting genes: MED15 PAX6 RNF126 TRIM27 TRIM29 TRIM35 USP14	12 interacting genes: ATP5F1C ATXN1 CTDP1 FHL3 MED25 MLLT6 PLSCR1 RELA SMAD2 SMAD3 TRIM11 UBC
Entrez ID		81559	51586
HPRD ID		07429	12117
Ensembl ID		ENSG00000154370	ENSG00000099917
Uniprot IDs		Q96F44	B7Z2H7 G3V1P5 Q6PKB8 Q96RN5
PDB IDs			2GUT
Enriched GO Terms of Interacting Partners?
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