TRIM11 and TRIM35

Data Source:
BioGRID (two hybrid)

		TRIM11	TRIM35
Description		tripartite motif containing 11	tripartite motif containing 35
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Nucleus Cytoplasm
	Molecular Function	Protein Binding Transcription Factor Binding Zinc Ion Binding Protein Domain Specific Binding Ubiquitin Protein Ligase Activity	Molecular_function Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Gene Expression Protein Ubiquitination Negative Regulation Of Viral Transcription Innate Immune Response Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Viral Entry Into Host Cell Negative Regulation Of Neurogenesis Defense Response To Virus Negative Regulation Of Viral Release From Host Cell	Apoptotic Process Protein Ubiquitination Positive Regulation Of Apoptotic Process Innate Immune Response Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Viral Release From Host Cell
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Interferon gamma signaling
Drugs
Diseases
GWAS		Hip circumference (psychosocial stress interaction) ( 25271088) Non-Richardson's syndrome vs Richardson's syndrome in progressive supranuclear palsy ( 30066433)	Chronotype ( 30696823) Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919) Lung cancer ( 28604730)
Interacting Genes		7 interacting genes: MED15 PAX6 RNF126 TRIM27 TRIM29 TRIM35 USP14	49 interacting genes: ADIPOQ BANP CABP2 COL8A1 DTX2 ENKD1 FNDC3B GNMT HNRNPA2B1 IGFN1 KANK2 LCK LMO1 MGAT5B NRF1 PAN2 PARD6B PDCD5 PHF24 PKM PPP2CA PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E QARS1 SHC3 SMARCB1 TCEANC TRAPPC6A TRIM10 TRIM11 TRIM5 TRIM55 TRIM63 TSG101 TSSK3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2K UBE2U UBE2W USP2 USP49 ZNF410
Entrez ID		81559	23087
HPRD ID		07429	15553
Ensembl ID		ENSG00000154370	ENSG00000104228
Uniprot IDs		Q96F44	E5RGB3 Q9UPQ4
PDB IDs
Enriched GO Terms of Interacting Partners?
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