CALU and APCS

Data Source:
HPRD (in vitro)

		CALU	APCS
Description		calumenin	amyloid P component, serum
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Sarcoplasmic Reticulum Lumen Melanosome	Extracellular Region Extracellular Space Nucleus Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	Calcium Ion Binding Protein Binding	Complement Component C1q Complex Binding Calcium Ion Binding Protein Binding Low-density Lipoprotein Particle Binding Carbohydrate Binding Identical Protein Binding Virion Binding Unfolded Protein Binding
	Biological Process	Biological_process Post-translational Protein Modification Cellular Protein Metabolic Process	Negative Regulation Of Acute Inflammatory Response Protein Folding Acute-phase Response Complement Activation, Classical Pathway Cellular Protein Metabolic Process Negative Regulation By Host Of Viral Process Negative Regulation By Host Of Viral Exo-alpha-sialidase Activity Negative Regulation By Host Of Viral Glycoprotein Metabolic Process Innate Immune Response Negative Regulation Of Monocyte Differentiation Negative Regulation Of Viral Entry Into Host Cell Negative Regulation Of Viral Process Chaperone-mediated Protein Complex Assembly Negative Regulation Of Wound Healing Negative Regulation Of Exo-alpha-sialidase Activity Negative Regulation Of Glycoprotein Metabolic Process
Pathways		Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Amyloid fiber formation
Drugs			Zinc Methyl 4,6-O-[(1R)-1-carboxyethylidene]-beta-D-galactopyranoside Bis-1,2-{[(Z)-2-carboxy-2-methyl-1,3-dioxane]-5-yloxycarbamoyl}-ethane BIS-1,2-{[(Z)-2CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBONYL}-PIPERAZINE Copper Zinc acetate
Diseases
GWAS		Atrial fibrillation ( 30061737) Intelligence (MTAG) ( 29326435) Moderate to vigorous physical activity levels ( 29899525) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397) Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer ( 32562552)	Blood protein levels ( 30072576 29875488 28240269) C-reactive protein ( 22939635)
Interacting Genes		9 interacting genes: APCS CSNK2A1 CTNNAL1 MFHAS1 PRMT5 UBE2I UBQLN1 UMPS ZPBP	18 interacting genes: ALX1 C1QA C4BPA CALU COL4A1 COPS5 CRP FCGR1A FCGR2B FCGR3A FCGR3B FN1 GK GOT2 GRB2 HES1 LAMA1 TG
Entrez ID		813	325
HPRD ID		04569	00101
Ensembl ID		ENSG00000128595	ENSG00000132703
Uniprot IDs		A0A024R755 B3KQF5 O43852 Q6IAW5	P02743 V9HWP0
PDB IDs			1GYK 1LGN 1SAC 2A3W 2A3X 2A3Y 2W08 3D5O 3KQR 4AVS 4AVT 4AVV 4AYU
Enriched GO Terms of Interacting Partners?
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