ANP32A and ADAP1

Data Source:
HPRD (in vitro)

		ANP32A	ADAP1
Description		acidic nuclear phosphoprotein 32 family member A	ArfGAP with dual PH domains 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Protein Binding Histone Binding	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Inositol 1,3,4,5 Tetrakisphosphate Binding Metal Ion Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Nucleocytoplasmic Transport Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of MRNA Stability	Cell Surface Receptor Signaling Pathway Regulation Of GTPase Activity Positive Regulation Of GTPase Activity
Pathways		HuR (ELAVL1) binds and stabilizes mRNA	Nuclear signaling by ERBB4
Drugs
Diseases
GWAS		Esophageal cancer ( 21642993)	Apolipoprotein A1 levels ( 32203549) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Platelet distribution width ( 32888494)
Interacting Genes		29 interacting genes: ADAP1 APEX1 ATXN1 AXIN1 CHAF1A E4F1 ELAVL1 H2AC20 H2BC21 H3-4 H3C1 H3C15 H4-16 H4C1 HSPB3 KPNA1 KPNA5 KPNA6 LHX3 MAP1B NSFL1C PCBP1 PGR PPARG PTPRC SET TAF1A THRB XPO1	24 interacting genes: ANP32A AP3B2 CSNK1A1 DVL3 GADD45A GOLGA2 GSK3B NCL PIK3CA PLEKHF2 PRKCA PRKCE PRKCI PRKCZ PRKD1 PSME3 PURA RANBP9 RPS9 SDCBP2 SF3A3 SRSF2 SUB1 SUPV3L1
Entrez ID		8125	11033
HPRD ID		09014	09733
Ensembl ID		ENSG00000140350	ENSG00000105963
Uniprot IDs		A0A384P5U2 P39687	A8K3A2 B4DUZ7 O75689
PDB IDs		2JE0 2JE1 4XOS	3FEH 3FM8 3LJU 3MDB
Enriched GO Terms of Interacting Partners?
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