ADAP1 and AP3B2

Data Source:
HPRD (in vitro)

		ADAP1	AP3B2
Description		ArfGAP with dual PH domains 1	adaptor related protein complex 3 subunit beta 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle	Golgi Apparatus AP-3 Adaptor Complex Clathrin-coated Vesicle Membrane Intracellular Vesicle Axon Cytoplasm
	Molecular Function	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Inositol 1,3,4,5 Tetrakisphosphate Binding Metal Ion Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Regulation Of GTPase Activity Positive Regulation Of GTPase Activity	Intracellular Protein Transport Anterograde Axonal Transport Vesicle-mediated Transport Anterograde Synaptic Vesicle Transport
Pathways		Nuclear signaling by ERBB4
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Platelet distribution width ( 32888494)	Lipoprotein-associated phospholipase A2 activity change in response to statin therapy ( 23118302) Schizophrenia ( 28991256) Tourette syndrome ( 30818990)
Interacting Genes		24 interacting genes: ANP32A AP3B2 CSNK1A1 DVL3 GADD45A GOLGA2 GSK3B NCL PIK3CA PLEKHF2 PRKCA PRKCE PRKCI PRKCZ PRKD1 PSME3 PURA RANBP9 RPS9 SDCBP2 SF3A3 SRSF2 SUB1 SUPV3L1	7 interacting genes: ADAP1 AP3S1 ATM CLTC CSNK1A1 ERBB2 RUFY1
Entrez ID		11033	8120
HPRD ID		09733	03699
Ensembl ID		ENSG00000105963	ENSG00000103723
Uniprot IDs		A8K3A2 B4DUZ7 O75689	F5GYB0 Q13367
PDB IDs		3FEH 3FM8 3LJU 3MDB
Enriched GO Terms of Interacting Partners?
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