THAP7 and LURAP1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		THAP7	LURAP1
Description		THAP domain containing 7	leucine rich adaptor protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nuclear Speck Nuclear Membrane Intracellular Membrane-bounded Organelle	Cytoplasm Cytosol Actomyosin Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Transcription Corepressor Binding DNA Binding Protein Binding Nucleosomal Histone Binding Methylated Histone Binding Identical Protein Binding Histone Deacetylase Binding Metal Ion Binding Protein N-terminus Binding Lysine-acetylated Histone Binding C2H2 Zinc Finger Domain Binding Phosphorylated Histone Binding General Transcription Initiation Factor Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Negative Regulation Of Histone Acetylation Negative Regulation Of Transcription, DNA-templated	Positive Regulation Of Cytokine Production Cell Migration Actomyosin Structure Organization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways
Drugs
Diseases
GWAS			Body mass index ( 26426971)
Interacting Genes		63 interacting genes: ANKRD28 APP CCDC136 CCDC85B CCNDBP1 CDC37 CYSRT1 DESI2 DVL3 EFEMP2 EHMT2 FBXO7 FHL3 FSD2 GABARAPL1 GNAI1 GOLGA2 GOLGA6L9 H3C1 H4C1 HCFC1 HDAC3 HOXA1 KRT27 KRT31 KRT34 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP17-1 KRTAP4-12 LDOC1 LNX1 LURAP1 LZTS2 MAGOHB MAP1LC3B MCC MDFI MID2 MTUS2 NBPF19 NOTCH2NLA NTAQ1 PELI2 PHC2 PHF19 PICK1 PIN1 PNMA2 PPP3CC SET TAF1B TFIP11 THAP11 TLE5 TPM3 TRAF1 TRAF2 TRAF5 ZDHHC17 ZRANB1	22 interacting genes: ABI2 AMOT BLOC1S6 CCDC112 CCDC185 CSNK1D DOCK10 DTNB HAUS1 HGS HMG20A KRT3 PRPF31 SHFL SNAP29 TCEANC THAP7 TPM3 TXLNB U2AF2 ZNF417 ZNF821
Entrez ID		80764	541468
HPRD ID		15500	18478
Ensembl ID		ENSG00000184436	ENSG00000171357
Uniprot IDs		Q9BT49	Q96LR2
PDB IDs
Enriched GO Terms of Interacting Partners?
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