THAP7 and PNMA2

Data Source:
BioGRID (two hybrid)

		THAP7	PNMA2
Description		THAP domain containing 7	PNMA family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nuclear Speck Nuclear Membrane Intracellular Membrane-bounded Organelle	Nucleolus
	Molecular Function	RNA Polymerase II Transcription Corepressor Binding DNA Binding Protein Binding Nucleosomal Histone Binding Methylated Histone Binding Identical Protein Binding Histone Deacetylase Binding Metal Ion Binding Protein N-terminus Binding Lysine-acetylated Histone Binding C2H2 Zinc Finger Domain Binding Phosphorylated Histone Binding General Transcription Initiation Factor Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Negative Regulation Of Histone Acetylation Negative Regulation Of Transcription, DNA-templated	Positive Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		63 interacting genes: ANKRD28 APP CCDC136 CCDC85B CCNDBP1 CDC37 CYSRT1 DESI2 DVL3 EFEMP2 EHMT2 FBXO7 FHL3 FSD2 GABARAPL1 GNAI1 GOLGA2 GOLGA6L9 H3C1 H4C1 HCFC1 HDAC3 HOXA1 KRT27 KRT31 KRT34 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP17-1 KRTAP4-12 LDOC1 LNX1 LURAP1 LZTS2 MAGOHB MAP1LC3B MCC MDFI MID2 MTUS2 NBPF19 NOTCH2NLA NTAQ1 PELI2 PHC2 PHF19 PICK1 PIN1 PNMA2 PPP3CC SET TAF1B TFIP11 THAP11 TLE5 TPM3 TRAF1 TRAF2 TRAF5 ZDHHC17 ZRANB1	32 interacting genes: BYSL CBX8 CCDC33 CDC37 CNNM3 ENKD1 FAM161A GPATCH2L HAPLN2 INO80B LRR1 MISP MORF4L2 NTAQ1 PPIG PRPF31 PSMA1 RNF6 RNF8 RPL9 RTP5 SCNM1 SDCBP THAP7 TOP3B TTLL10 ZNF408 ZNF417 ZNF587 ZNF669 ZNF688 ZNF785
Entrez ID		80764	10687
HPRD ID		15500	04915
Ensembl ID		ENSG00000184436	ENSG00000240694
Uniprot IDs		Q9BT49	Q5U5Z3 Q9UL42
PDB IDs
Enriched GO Terms of Interacting Partners?
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