COASY and POU3F2

Data Source:
BioGRID (affinity chromatography technology)

		COASY	POU3F2
Description		Coenzyme A synthase	POU class 3 homeobox 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Mitochondrial Matrix Extracellular Exosome	Chromatin Nucleoplasm Transcription Regulator Complex
	Molecular Function	Dephospho-CoA Kinase Activity Pantetheine-phosphate Adenylyltransferase Activity Protein Binding ATP Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Coenzyme A Biosynthetic Process Phosphorylation	Regulation Of Transcription By RNA Polymerase II Nervous System Development Positive Regulation Of Cell Population Proliferation Epidermis Development Negative Regulation Of Gene Expression Astrocyte Development Cerebral Cortex Radially Oriented Cell Migration Forebrain Ventricular Zone Progenitor Cell Division Hypothalamus Cell Differentiation Neurohypophysis Development Myelination In Peripheral Nervous System Neuron Differentiation Positive Regulation Of Multicellular Organism Growth Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Commitment Neuron Fate Specification Neuron Development Regulation Of Axonogenesis Cellular Response To Organic Substance
Pathways		Coenzyme A biosynthesis	EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS		Medication use (drugs used in diabetes) ( 31015401) Metabolic syndrome ( 31589552)	Bipolar disorder ( 24618891 27329760) Body size at age 10 ( 32376654) Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125) Chronotype ( 30696823) Educational attainment ( 25201988) Erectile dysfunction ( 30583798) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels ( 32203549) Intelligence ( 28530673) Metabolite levels ( 23823483) Morning person ( 30696823) Number of sexual partners ( 30643258) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965) QT interval (drug interaction) ( 23459443) Regular attendance at a religious group ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		11 interacting genes: APP BTK CNTROB KIAA1958 KRT20 LYN PJA1 RPS6KB1 RPS6KB2 SRC SYK	11 interacting genes: EP300 GTF2B NFYA NFYB NFYC PAX3 POU3F4 PQBP1 SOX10 SOX11 TBP
Entrez ID		80347	5454
HPRD ID		13080	02734
Ensembl ID		ENSG00000068120	ENSG00000184486
Uniprot IDs		Q13057	P20265
PDB IDs
Enriched GO Terms of Interacting Partners?
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