POU3F2 and POU3F4

Data Source:
HPRD (in vitro)

		POU3F2	POU3F4
Description		POU class 3 homeobox 2	POU class 3 homeobox 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Transcription Regulator Complex	Chromatin Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Nervous System Development Positive Regulation Of Cell Population Proliferation Epidermis Development Negative Regulation Of Gene Expression Astrocyte Development Cerebral Cortex Radially Oriented Cell Migration Forebrain Ventricular Zone Progenitor Cell Division Hypothalamus Cell Differentiation Neurohypophysis Development Myelination In Peripheral Nervous System Neuron Differentiation Positive Regulation Of Multicellular Organism Growth Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Commitment Neuron Fate Specification Neuron Development Regulation Of Axonogenesis Cellular Response To Organic Substance	Regulation Of Transcription By RNA Polymerase II Brain Development Sensory Perception Of Sound Cochlea Morphogenesis Negative Regulation Of Mesenchymal Cell Apoptotic Process
Pathways		EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS		Bipolar disorder ( 24618891 27329760) Body size at age 10 ( 32376654) Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125) Chronotype ( 30696823) Educational attainment ( 25201988) Erectile dysfunction ( 30583798) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels ( 32203549) Intelligence ( 28530673) Metabolite levels ( 23823483) Morning person ( 30696823) Number of sexual partners ( 30643258) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965) QT interval (drug interaction) ( 23459443) Regular attendance at a religious group ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258)	Chronotype ( 30696823) Heschl's gyrus morphology ( 25130324)
Interacting Genes		11 interacting genes: EP300 GTF2B NFYA NFYB NFYC PAX3 POU3F4 PQBP1 SOX10 SOX11 TBP	4 interacting genes: HNRNPU POU3F1 POU3F2 POU3F3
Entrez ID		5454	5456
HPRD ID		02734	02076
Ensembl ID		ENSG00000184486	ENSG00000196767
Uniprot IDs		P20265	A0A2R8Y739 P49335
PDB IDs
Enriched GO Terms of Interacting Partners?
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