MLLT10 and MLLT1

Data Source:
BioGRID (affinity chromatography technology, two hybrid)
HPRD (two hybrid)

		MLLT10	MLLT1
Description		MLLT10 histone lysine methyltransferase DOT1L cofactor	MLLT1 super elongation complex subunit
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Protein-containing Complex	Fibrillar Center Nucleoplasm Cytosol Transcription Elongation Factor Complex
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Nucleosome Binding Histone Binding Metal Ion Binding	Protein Binding
	Biological Process	Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity
Pathways			Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases			Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Adult body size ( 32376654) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 23535729) Epithelial ovarian cancer ( 25581431) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Gallstone disease ( 30504769) Hand grip strength ( 29691431) Lateral ventricular volume in normal aging ( 30258056) Meningioma ( 21804547) Metabolic syndrome ( 31589552) Multiple sclerosis ( 31604244) Multisite chronic pain ( 31194737) Oily fish consumption ( 32066663) Ovarian cancer ( 23535730) Pork consumption ( 32066663) Raw vegetable consumption ( 32066663) Subcutaneous adipose tissue ( 26480920) Urinary albumin-to-creatinine ratio ( 31630189) Urinary sodium excretion ( 31409800)	Monocyte percentage of white cells ( 32888494) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 27021288)
Interacting Genes		15 interacting genes: DISC1 DOT1L FOXI1 HNF1B HPCA MLLT1 NCALD NDEL1 POU2F1 POU6F2 RBPMS RGPD5 SS18 VEZF1 YEATS4	12 interacting genes: AFF1 AFF4 ALKBH4 ARID1A BMI1 CBX8 H1-5 H3-4 MLLT10 PAF1 WDR5 YIF1A
Entrez ID		8028	4298
HPRD ID		03874	15933
Ensembl ID		ENSG00000078403	ENSG00000130382
Uniprot IDs		P55197 Q59EQ6 Q6N002	Q03111
PDB IDs		5DAG 5DAH 6CKN 6CKO 6JN2	5J9S 6HPW 6HPX 6HPY 6HPZ 6HQ0 6HT0 6HT1 6T1I 6T1J 6T1L 6T1M 6T1N 6T1O
Enriched GO Terms of Interacting Partners?
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