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STAM and TIMM8A
Data Source:
HPRD
(in vitro, in vivo, two hybrid)
STAM
TIMM8A
Description
signal transducing adaptor molecule
translocase of inner mitochondrial membrane 8A
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Early Endosome Membrane
ESCRT-0 Complex
Intracellular Membrane-bounded Organelle
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Intermembrane Space
Molecular Function
Protein Binding
Ubiquitin-like Protein Ligase Binding
Protein Binding
Identical Protein Binding
Metal Ion Binding
Biological Process
Signal Transduction
Endosomal Transport
Macroautophagy
Protein Deubiquitination
Multivesicular Body Assembly
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Membrane Organization
Positive Regulation Of Exosomal Secretion
Regulation Of Extracellular Exosome Assembly
Nervous System Development
Chaperone-mediated Protein Transport
Pathways
EGFR downregulation
Metalloprotease DUBs
Negative regulation of MET activity
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
InlB-mediated entry of Listeria monocytogenes into host cell
Endosomal Sorting Complex Required For Transport (ESCRT)
Mitochondrial protein import
Drugs
Diseases
Mohr-Tranebjaerg syndrome
GWAS
Interacting Genes
20 interacting genes:
ARRB1
HGS
JAK1
JAK2
JAK3
MAP3K1
PJA1
PMEPA1
PPP1CA
PPP1CC
RFFL
STAMBP
TIMM8A
TRIM54
TRIM55
TRIM63
UBC
USP15
USP28
USP8
8 interacting genes:
ARID3A
C1QTNF2
CAVIN3
KRT15
OIP5
STAM
STAM2
TIMM13
Entrez ID
8027
1678
HPRD ID
03542
02287
Ensembl ID
ENSG00000136738
ENSG00000126953
Uniprot IDs
B4DZT2
Q92783
A0A2R8YDA8
O60220
PDB IDs
2L0A
3F1I
3LDZ
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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