SVEP1 and ATF7IP

Data Source:
HPRD (two hybrid)

		SVEP1	ATF7IP
Description		sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	activating transcription factor 7 interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Membrane	Nucleus Nucleoplasm Transcription Regulator Complex Cytosol Nuclear Body
	Molecular Function	Calcium Ion Binding	Transcription Corepressor Activity Protein Binding ATPase Activity
	Biological Process	Cell Adhesion	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Viral Process Regulation Of Protein Stability Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Protein Stabilization Positive Regulation Of DNA Methylation-dependent Heterochromatin Assembly
Pathways			PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Bipolar disorder ( 20351715) Blood protein levels ( 30072576 29875488) Coronary artery disease ( 29212778) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Diastolic blood pressure ( 27841878) Height ( 28552196) Longevity ( 20834067) Mean arterial pressure ( 27618448) Mean platelet volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252) Pulse pressure ( 27841878) Spontaneous preterm birth without premature rupture of membranes ( 31194736) Systolic blood pressure ( 27841878 27618448 30578418) Type 2 diabetes (dietary heme iron intake interaction) ( 23386860)	Breast cancer ( 24143190) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Height ( 31562340) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Leukocyte telomere length ( 32109421) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Prostate-specific antigen levels ( 23359319) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 28604728 28604732 23666240)
Interacting Genes		6 interacting genes: ATF7IP MTNR1A SKIL SMAD3 SMAD9 ZFYVE9	70 interacting genes: A2M ACTB ACTG1 AP1B1 CADM1 CEP250 COL4A2 CREB1 CREBBP CSPG4 DISC1 DMTF1 DNM2 EHMT2 EPG5 FLNB FLT4 GMEB1 GTF2E2 GTF2F1 GTF2H1 HEYL HLA-B HSPG2 KIF13A KRT7 LAMA4 LAMA5 LAMC1 LUC7L2 MACF1 MBD1 MCAM MED4 MRI1 NOMO1 NPR1 PAPPA PAPPA2 PCDH1 PEX6 PIAS3 PKD1 PLEKHB2 POLR2C POLR2D POLR2G PRSS8 PSG3 QRICH1 RPS3A RRBP1 SENP3 SETDB1 SLC12A4 SMAD4 SP1 SPTBN1 SREBF2 STBD1 STRN SUMO2 SUSD1 SVEP1 TRIP12 TTC3 UBE2I ZBTB6 ZNF350 ZNF518A
Entrez ID		79987	55729
HPRD ID		12942	09811
Ensembl ID		ENSG00000165124	ENSG00000171681
Uniprot IDs		B3KQM1 Q4LDE5 Q5JB40	A0A024RAY1 B3KNI7 B3KQF8 Q6VMQ6
PDB IDs			2RPQ
Enriched GO Terms of Interacting Partners?
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