ATF7IP and MRI1

Data Source:
HPRD (two hybrid)

		ATF7IP	MRI1
Description		activating transcription factor 7 interacting protein	methylthioribose-1-phosphate isomerase 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Cytosol Nuclear Body	Fibrillar Center Nucleoplasm Cytosol Cell Projection
	Molecular Function	Transcription Corepressor Activity Protein Binding ATPase Activity	Protein Binding Identical Protein Binding S-methyl-5-thioribose-1-phosphate Isomerase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Viral Process Regulation Of Protein Stability Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Protein Stabilization Positive Regulation Of DNA Methylation-dependent Heterochromatin Assembly	L-methionine Salvage From S-adenosylmethionine L-methionine Salvage From Methylthioadenosine
Pathways		PKMTs methylate histone lysines	Methionine salvage pathway
Drugs
Diseases
GWAS		Breast cancer ( 24143190) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Height ( 31562340) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Leukocyte telomere length ( 32109421) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Prostate-specific antigen levels ( 23359319) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 28604728 28604732 23666240)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		70 interacting genes: A2M ACTB ACTG1 AP1B1 CADM1 CEP250 COL4A2 CREB1 CREBBP CSPG4 DISC1 DMTF1 DNM2 EHMT2 EPG5 FLNB FLT4 GMEB1 GTF2E2 GTF2F1 GTF2H1 HEYL HLA-B HSPG2 KIF13A KRT7 LAMA4 LAMA5 LAMC1 LUC7L2 MACF1 MBD1 MCAM MED4 MRI1 NOMO1 NPR1 PAPPA PAPPA2 PCDH1 PEX6 PIAS3 PKD1 PLEKHB2 POLR2C POLR2D POLR2G PRSS8 PSG3 QRICH1 RPS3A RRBP1 SENP3 SETDB1 SLC12A4 SMAD4 SP1 SPTBN1 SREBF2 STBD1 STRN SUMO2 SUSD1 SVEP1 TRIP12 TTC3 UBE2I ZBTB6 ZNF350 ZNF518A	4 interacting genes: ATF7IP COG6 PICK1 PLEKHF2
Entrez ID		55729	84245
HPRD ID		09811	14548
Ensembl ID		ENSG00000171681	ENSG00000037757
Uniprot IDs		A0A024RAY1 B3KNI7 B3KQF8 Q6VMQ6	Q9BV20
PDB IDs		2RPQ	4LDQ 4LDR
Enriched GO Terms of Interacting Partners?
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